提問者：
想養一隻貓
等級：
助理工程師
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464
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http://www.cfsan.fda.gov/~dms/melamra.html#execsum
Accumulation of melamine in the edible tissue of animals (pork, poultry and fish) consuming the contaminated feed at the levels reported in feed to date is considered highly unlikely. For the purpose of this assessment it is assumed that all edible tissues contain 50 ppb melamine. The basis for using such a level comes from reports from FDA and FSIS of trace levels of melamine in tissues from some hogs that consumed the suspect feed containing rice protein. The 50 ppb level represents a conservative estimate of the Limit of Detection (LOD) for the methods employed; a value that will ensure that the exposure scenarios are in turn conservative. (The LOD is the level below which a contaminant cannot be measured with current analytical methods.) Currently this method is designed to only detect melamine in meat; however, it is presumed that the other MCs are present in the tissue.
這是50ppb的來源
以下還有老鼠實驗13週的描述
Available publications report the most sensitive value for oral 50% lethal dose (LD50) is 3161 mg/kg in rats.1, 2 The most recent reported no-observed-adverse-effect-levels (NOAELs) are 63 mg/kg bw/day (13 weeks, oral with feed, in rats); 240 mg/kg bw/day (28 days, oral with feed, in rats); 417 mg/kg bw/day (14 days, oral with feed, in rats); and 1600 mg/kg bw/day (13 weeks, oral with feed, in mice).2 In addition, the most sensitive calculated NOAELs for oral reproductive and developmental toxicity in rats are 400 mg/kg bw/day (maternal) and 1060 mg/kg bw/day (fetal), respectively.
我們的衛生署應該是根據這份資料做出2.5ppm的決策
不過, 我的看法, 是該報告從頭到尾都沒說這東西是人類可吃的
只是從一些途徑, 如食物或包裝殘留間接被人吃下後, 建議的安全容許量
所以, 結論是開放2.5ppm容許量也許是不智的決定
因為這有可能刺激黑心廠商在合法範圍內開發更多黑心商品
---反正有容許值, 加了可以省成本, 為何不做呢?
如果我的認知有錯, 請專家指點吧, 謝謝
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